Patents & Licensing

• New Molecular Resists for Electron Beam Lithography
  • Continuing miniaturisation of semiconductor devices poses significant challenges to current photolithographic production techniques. Next-generation techniques are being considered by the market for extending beyond the 30 nm mode, • In order for these new resist methods to be effective at very low minimum feature size, the resist material itself must be adapted. • A novel molecular resist, has been produced with improved sensitivity which is suitable for use with E. U.V.
  
  
• Cloning – A New Nuclear Transfer Method
  Current methods transfer nucleus and mitochondrial DNA into the host cell which has its own mtDNA population. New method ensure that by depleting donor cells embryos contain only oocyte mtDNA giving rise to a normal homoplastic cell.
  
  
• Rapid Production of Ceramic Moulds for Investment Casting
  Investment casting requires building of a mould around a wax pattern of the required casting. Mould building is a time consuming process involving drying of layers ceramic materials. A new rapid shell build method using super-absorbent polymers reduces shell build time.
  
  
• Novel Combined Chemotherapy
  Improved cancer chemotherapy through the combination of histone deacetylase inhibitors and nuclear receptor ligands
  
  
• A new genetic test for severe erosive Rheumatoid Arthritis
  A polymorphism in CDO gene is predictive for severe erosive Rheumatoid Arthritis and can be easily screened for by routine testing methods
  
  
• Histone Antibody Screening
  Histones are involve in the coiling and packaging of DNA into chromosomes and also regulate genes. Research into histones is heavily dependent on antibodies. These antibodies can be of variable quality and usefulness. Researchers at UoB have developed an assay which allows the binding properties of histone antibodies to be characterised.
  
  
• Light Chain Assay
  For diagnosis and monitoring of multiple myeloma (MM). A monoclonal diagnostic for ? and ? free light chain antibodies.
  
  
• New Cancer Drug Target
  A groundbreaking new molecular design for drugs which bonds to newly discovered binding sites within the DNA helix and allows precise targeting of metallo compounds for cancer therapy. This will potentially allow development of a new class of groundbreaking anti cancer drugs with improved tolerance and efficacy.
  
  
• Screen for Assessing Endocrine Disruption Potential of Widely Used Chemicals
  A carefully selected portfolio of in vitro tests which together provide initial data on the endocrine disruption potential of chemicals
  
  
• Euclid Interferometer
  EUCLID is a compact laser interferometric measuring device capable of sensing at the pico metre level (10 to power of -12)
  
  
• Fibre Optic Sensors
  An rugged optical fibre device suitable for embedding into composite components and structures in production or use, to monitor parameters such as load, stress, strain, vibration, change of chemical composition and temperature.
  
  
• Promoting Neuronal Tissue Repair after Injury or Disease
  NM23 – an amino acid residue with proven ability to promote neuronal growth
  
  
• Low Fat Emulsion for use in reduced fat food production
  A method for producing air filled protein coated droplets which can be substituted for fat in emulsions to enable production of low fat foods.
  
  
• Vaccine for non Typhoidal Salmonella
  OMPD an outer membrane protein present in non-typhoidal salmonella (NTS) could lead to the development of a novel vaccine. Salmonella is a dangerous infection that causes high mortality in infants in sub Saharan Africa
  
  
• Urinary Markers of Adrenal Tumors
  A set of urinary markers has been identified which can differentiate adrenocortical carcinomas (ACC) which are rare highly malignant tumors with poor prognosis from adrenocortical adenomas (ACA) which are benign and found in 2-3% of the population.
  
  
• Platinum Recovery from Road Dust
  A method of recovering platinum group metals which originate from catalytic converters from roadside dust.
  
  
• An Early Diagnostic for Muscular Dystrophy
  An early diagnostic test for muscular dystrophy which allows earlier treatment which has the potential to extend and improve quality of life.
  
  
• Reduced Fat chocolate
  A method of incorporating water into chocolate manufacture to reduce the fat content whilst maintaining eating quality.
  
  
• Using Polymers to Liberate Cell Membrane Proteins
  A method for combining polymers with cell membrane lipids to produce disk shaped nanoparticles, which are a useful tool in cell research and drug discovery
  
  
• Assessing the Impact of Stroke on Cognitive Abilities
  A set of psychological tests that assesses the cognitive abilities of individuals following a stroke and is useful as a tool to predict recovery and measure outcome at follow-up.
  
  
• Carbon nanowires in advanced electronics
  A method has been developed so fullerene derivatives (C60 ) can be formed into conductive nanowires and used in electronic device prototyping and organic electronics
  
  
• Reconfigurable Antennae for Wireless Communications
  A reconfigurable antenna designed for current and future wireless communication systems. The antenna system is primarily geared for hand held mobile devices such as mobile telephones, laptops, PDA etc.